The endocannabinoid system (ECS) is a complex system that is responsible for relaying messages throughout the body. If you keep up to date with JuJu Royal blogs, then you are most likely familiar with the term “endocannabinoid system”. This is a cell-signaling system that was discovered at the end of the 20th century while researchers were investigating the impact of THC and related products on the human body. The ECS has a wide range of functions that include regulating memory, appetite, mood, sleep, fertility, and reproduction. The ECS remains active both with and without the presence of cannabis products.

Endocannabinoids are molecules that keep the body moving smoothly and are produced by the body as needed. The main two endocannabinoids identified by researchers so far are anandamide (AEA) and 2-arachidonoylglyerol (2-AG). Endocannabinoid receptors can be found throughout the entire human body. The main endocannabinoid receptors are CB1 and CB2. Endocannabinoids can bind to either receptor and the effect depends on which receptor and where it is located.

Research is ongoing concerning the relation of CBD to the ECS. CBD binds differently to CB1 and CB2 receptors than THC. CB1 receptors, one of the most common receptors in the whole nervous system, are necessary for a successfully functioning brain. These specific brain receptors are also responsible for the psychoactive properties of cannabis when they bind with THC. CB2 receptors are commonly found in the cells of the human immune system. CBD uniquely interacts with the ECS because it influences other receptors unlike THC.

All studies in the ECS direct toward one common understanding: the ECS is important and easy to disrupt. Therefore, common factors such as diet and sleep patterns can impact the ECS. There are more than 100 Phytocannabinoids, all of which can have a different interaction with your body’s CB receptors. A phytocannabinoid is any cannabinoid produced in the trichomes of a cannabis plant. Cannabinoids are commonly divided into two categories, phytocannabinoids and endocannabinoids. Phytocannabinoids are those produced by plants and endocannabinoids are those produced by mammals. Both activate the body’s ECS when they bind to the cannabinoid receptors. Endocannabinoids specifically activate a homeostatic effect that balances the health of the body. The ECS is full of surprises and holds much potential for the world of CBD and beyond!

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